Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563608 | 1.00 | HTT (0.57) | HTTBRD4CREBBPALDH1A1TRPV1 | |
| SCHEMBL13131121 | 1.00 | HTT (0.57) | HTTBRD4CREBBPALDH1A1TRPV1 | |
| SCHEMBL26962614 | 0.86 | TRPV1 (0.50) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL27125516 | 0.86 | TRPV1 (0.50) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL4226634 | 0.84 | TRPV1 (0.54) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL4226632 | 0.84 | TRPV1 (0.54) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL31316828 | 0.81 | TRPV1 (0.49) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL599782 | 0.81 | TRPV1 (0.49) | BRD4CREBBPTRPV1DRD2HTR2A | |
| SCHEMBL20622055 | 0.81 | TRPV1 (0.49) | BRD4CREBBPTRPV1CNR1CNR2 | |
| SCHEMBL10454044 | 0.81 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848107-A | Compounds and their use as PDE4 activators | 米罗尼德有限公司 | 2023-10-03 | — | — | CN | disclosed |