SCHEMBL3056487

SCHEMBL3056487

CC(=O)[C@@](O)(C(=O)Cl)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5802631 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8584655 0.89
SCHEMBL5859311 0.83 PDE4A (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29162767 0.83 PDE4A (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL16798768 0.83 PDE4A (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL29020598 0.82 LMNA (0.46) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL723573 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL2789359 0.81 USP2 (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL941684 0.81 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4058224 0.81 USP2 (0.37) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9134302-B2 Analyte detection utilizing polynucleotide sequences, composition, process and kit ENZO DIAGNOSTICS, INC. (US) 2015-09-15 US disclosed
US-20100273145-A1 ASSAY METHOD UTILIZING POLYNUCLEOTIDE SEQUENCES ENZO BIOCHEM, INC. (US) 2010-10-28 US disclosed
EP-0611828-B1 Composition for use in an assay method utilizing polynucleotide sequences ENZO BIOCHEM INC (US) 2000-11-08 EP disclosed
EP-0128332-B1 Assay method utilizing polynucleotide sequences ENZO BIOCHEM INC (US) 1995-08-02 EP disclosed
EP-0611828-A1 Composition for use in an assay method utilizing polynucleotide sequences ENZO BIOCHEM, INC. (US) 1994-08-24 EP disclosed
EP-0128332-A1 Assay method utilizing polynucleotide sequences ENZO BIOCHEM, INC. (US) 1984-12-19 EP disclosed