Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 16/20 | 0.33 |
| ▸ | JAK1 | P23458 | 15/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566490 | 0.83 | PDK2 (0.41) | FEN1JAK3JAK1 | |
| SCHEMBL30566481 | 0.81 | JAK1 (0.35) | JAK3JAK1 | |
| SCHEMBL24576990 | 0.80 | IKBKE (0.41) | FEN1JAK3JAK1 | |
| SCHEMBL29759678 | 0.79 | KDM1A (0.38) | JAK3JAK1 | |
| SCHEMBL30566577 | 0.78 | RIPK2 (0.32) | JAK3JAK1 | |
| SCHEMBL24576870 | 0.78 | MKNK1 (0.41) | JAK3JAK1 | |
| Hydrochloric Acid SCHEMBL30566474 | 0.77 | MKNK1 (0.41) | JAK3JAK1 | |
| SCHEMBL29759773 | 0.75 | JAK1 (0.40) | JAK3JAK1 | |
| SCHEMBL30566568 | 0.75 | JAK1 (0.35) | JAK3JAK1 | |
| SCHEMBL30566512 | 0.74 | JAK3 (0.38) | TGFBR1JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |