Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387001 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386999 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL31595519 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL26264484 | 0.92 | PPARG (0.45) | MEN1KMT2ALMNAPYGLRAB9A | |
| SCHEMBL26264485 | 0.92 | PPARG (0.45) | MEN1KMT2ALMNAPYGLRAB9A | |
| SCHEMBL30567109 | 0.89 | MTNR1B (0.48) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386646 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386647 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL31595489 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL30567131 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| CN-119013247-A | PCNA inhibitor and use thereof | 希望之城 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |