Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387001 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386999 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL30567108 | 1.00 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL26264484 | 0.92 | PPARG (0.45) | MEN1KMT2ALMNAPYGLRAB9A | |
| SCHEMBL26264485 | 0.92 | PPARG (0.45) | MEN1KMT2ALMNAPYGLRAB9A | |
| SCHEMBL30567109 | 0.89 | MTNR1B (0.48) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386646 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL25386647 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL31595489 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA | |
| SCHEMBL30567131 | 0.84 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | UNITED STATES GOVERNMENT | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | PCNA, MKI67, PCLAF | MTNR1B 4532/4885PYGM 2611/4885MEN1 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.