SCHEMBL30567341

SCHEMBL30567341

Nc1nc2c(ncn2[C@@H]2O[C@H](COB(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.69
NT5E P21589 1/20 0.69
GSK3A P49840 2/20 0.65
RPS6KA3 P51812 2/20 0.65
MAPK14 Q16539 2/20 0.65
TGM2 P21980 1/20 0.64
PNP P00491 1/20 0.62
KRAS P01116 5/20 0.58
FUT5 Q11128 1/20 0.57
HPGD P15428 1/20 0.57
IMPDH2 P12268 2/20 0.56
IMPDH1 P20839 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2'-Beta-Methyl-Guanosine SCHEMBL5972612 0.89 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL9059278 0.89 HINT1 (0.70) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL3514472 0.89 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL17355882 0.89 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL3970953 0.89 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL186043 0.88 HINT1 (0.69) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL7111080 0.88 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
2'-Beta-Methyl-Guanosine SCHEMBL11965261 0.88 HINT1 (0.75) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2014087 0.88 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
2'-Beta-Methyl-Guanosine SCHEMBL116165 0.88 HINT1 (0.75) HINT1NT5EGSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121466476-A Oral ulcer intelligent microneedle patch based on guanosine vesicle slow release and preparation method thereof 中山大学附属口腔医院 2026-02-06 CN disclosed
CN-120168708-A Epigallocatechin-3-gallate loaded guanylate hydrogel as well as preparation method and application thereof 山西师范大学 2025-06-20 CN disclosed
CN-119455901-A Preparation method of blood perfusion diagnosis and treatment device based on guanosine supermolecular gel 广州医科大学附属第一医院(广州呼吸中心) 2025-02-18 CN disclosed
CN-116741306-A Nucleoside derivative gel forming capacity prediction model based on machine learning 四川大学 2023-09-12 CN disclosed