Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.52 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567365 | 1.00 | MEN1 (0.56) | MEN1KMT2ASIRT2NPC1CYP2C19 | |
| SCHEMBL30567367 | 0.85 | MAPT (0.68) | MEN1KMT2ASIRT2MAPTALOX15 | |
| SCHEMBL848485 | 0.85 | MAPT (0.68) | MEN1KMT2ASIRT2MAPTALOX15 | |
| SCHEMBL10936401 | 0.84 | MEN1 (0.58) | MEN1KMT2ASIRT2MAPTLMNA | |
| SCHEMBL8052123 | 0.84 | MEN1 (0.58) | MEN1KMT2ASIRT2NPC1RAB9A | |
| SCHEMBL30294594 | 0.84 | FABP4 (0.71) | MEN1KMT2ACDC7DAPK3PAK4 | |
| SCHEMBL354430 | 0.84 | FABP4 (0.71) | MEN1KMT2ACDC7DAPK3PAK4 | |
| SCHEMBL22853361 | 0.83 | MAPT (0.76) | KMT2ASIRT2CYP2C19CDC7DAPK3 | |
| SCHEMBL7833932 | 0.83 | AKR1C3 (0.44) | MEN1KMT2ACDK2MAPTAKR1C3 | |
| SCHEMBL6620978 | 0.83 | AKR1C3 (0.57) | MEN1KMT2ASIRT2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589406-A | Preparation method of polysubstituted acridine derivative | 深圳职业技术学院 | 2023-08-15 | — | — | CN | disclosed |
| EP-0783505-B1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | NOVARTIS AG (CH) | 2001-03-07 | — | — | EP | disclosed |
| US-5869485-A | Pyrrolo 2,3-d!pyrimidines and their use | NOVARTIS FINANCE CORP. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0783505-A1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | Novartis AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010028-A1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | NOVARTIS AG (CH) | 1996-04-04 | — | — | WO | disclosed |