Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056795 | 0.92 | KMT2A (0.62) | KMT2AMEN1PDE4BMAPTLMNA | |
| SCHEMBL9416605 | 0.91 | LMNA (0.75) | KMT2AMEN1PDE4BPDE4DMAPT | |
| SCHEMBL3055130 | 0.90 | PDE4B (0.66) | KMT2AMEN1PDE4BMAPTLMNA | |
| SCHEMBL3046120 | 0.88 | KMT2A (0.63) | KMT2AMEN1PDE4BPDE4DMAPT | |
| SCHEMBL3041866 | 0.88 | KMT2A (0.62) | KMT2AMEN1PDE4BMAPTLMNA | |
| SCHEMBL3056571 | 0.85 | KDM4E (0.69) | KMT2AMEN1PDE4BMAPTLMNA | |
| SCHEMBL9667825 | 0.85 | CHRNA7 (0.69) | KMT2AMEN1MAPTCHRNA7GPR183 | |
| SCHEMBL9668362 | 0.85 | CHRNA7 (0.69) | KMT2AMEN1MAPTCHRNA7GPR183 | |
| SCHEMBL3052486 | 0.84 | MAPK1 (0.64) | KMT2AMEN1PDE4BPDE4DMAPT | |
| SCHEMBL7893969 | 0.83 | KMT2A (0.85) | KMT2AMEN1PDE4BPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | claimed |
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | KMT2A 924/4885MEN1 305/4885PDE4B 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.