Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.64 |
| ▸ | GPR183 | P32249 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667825 | 0.87 | CHRNA7 (0.69) | KDM4EHSD17B10ALOX15CHRNA7GPR183 | |
| SCHEMBL9668362 | 0.87 | CHRNA7 (0.69) | KDM4EHSD17B10ALOX15CHRNA7GPR183 | |
| SCHEMBL9416605 | 0.86 | LMNA (0.75) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3056795 | 0.85 | KMT2A (0.62) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3041866 | 0.85 | KMT2A (0.62) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3056740 | 0.85 | KMT2A (0.68) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3055130 | 0.84 | PDE4B (0.66) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3046120 | 0.82 | KMT2A (0.63) | KDM4EHSD17B10ALOX15PDE4BCHRNA7 | |
| SCHEMBL3052611 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10ALOX15PDE4BKMT2A | |
| SCHEMBL9416631 | 0.81 | KMT2A (0.76) | KDM4EHSD17B10ALOX15CHRNA7GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | claimed |
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | KDM4E 1083/4885HSD17B10 1303/4885ALOX15 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.