SCHEMBL10000745

SCHEMBL10000745

O=C(O)c1ccnc(-c2cccc(-c3ccccn3)n2)c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5C P41229 8/20 0.87
KDM4C Q9H3R0 8/20 0.87
KDM4A O75164 7/20 0.87
KDM4E B2RXH2 5/20 0.87
KDM2A Q9Y2K7 4/20 0.87
KDM3A Q9Y4C1 4/20 0.87
KDM6B O15054 3/20 0.87
P4HA1 P13674 1/20 0.59
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
ALPL P05186 1/20 0.58
HSP90AA1 P07900 1/20 0.58
ALPI P09923 1/20 0.58
ALPG P10696 1/20 0.58
ALOX15 P16050 1/20 0.58
MAPK1 P28482 1/20 0.58
CCR1 P32246 1/20 0.58
HTT P42858 1/20 0.58
CCR5 P51681 1/20 0.58
CCR8 P51685 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766771 1.00 KDM5C (0.87) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL863220 0.94 KDM5C (0.87) KDM5CKDM4CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL21551506 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL913277 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL29562841 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL3941503 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL12131386 0.93 KDM5C (0.74) KDM5CKDM4CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL8358045 0.92 KDM4C (0.96) KDM5CKDM4CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL3954422 0.92 KDM4C (0.96) KDM5CKDM4CKDM4AKDM4EKDM2A
Benzoic Acid SCHEMBL30567494 0.92 KDM4C (0.96) KDM5CKDM4CKDM4AKDM4EKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113281500-B Magnetic bead for single molecule detection and preparation method thereof 深圳市光与生物科技有限公司 2022-07-12 CN disclosed
CN-113281500-A Magnetic bead for single molecule detection and preparation method thereof 深圳市光与生物科技有限公司 2021-08-20 CN disclosed
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2012-05-10 US disclosed
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2012-05-10 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME MLX, PRXL2A, MSL1 KDM5C 917/4885KDM4C 724/4885KDM4A 770/4885
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME MLX, PRXL2A, MSL1 KDM5C 907/4885KDM4C 733/4885KDM4A 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.