Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 10/20 | 0.47 |
| ▸ | CALCR | P30988 | 10/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591906 | 0.93 | GRB2 (0.46) | RAMP3CALCROPRM1OPRK1GRB2 | |
| SCHEMBL30509906 | 0.90 | OPRM1 (0.52) | RAMP3CALCROPRM1OPRK1NMUR2 | |
| SCHEMBL29379382 | 0.90 | NTSR2 (0.48) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL31416061 | 0.89 | RAMP3 (0.51) | RAMP3CALCROPRM1OPRK1NMUR2 | |
| SCHEMBL29629002 | 0.89 | GRB2 (0.50) | RAMP3CALCROPRM1OPRK1GRB2 | |
| SCHEMBL29437933 | 0.89 | RAMP3 (0.49) | RAMP3CALCROPRM1OPRK1NMUR2 | |
| SCHEMBL31031464 | 0.88 | OPRM1 (0.53) | RAMP3CALCROPRM1OPRK1NMUR2 | |
| SCHEMBL29701311 | 0.88 | OPRM1 (0.46) | RAMP3CALCROPRM1OPRK1GRB2 | |
| SCHEMBL30307576 | 0.88 | NRP1 (0.47) | OPRM1GRB2NMUR2NMUR1 | |
| SCHEMBL31034440 | 0.87 | NRP1 (0.44) | RAMP3CALCROPRM1OPRK1GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-22 | — | — | US | disclosed |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2024-01-25 | — | — | US | disclosed |
| CN-116601290-A | Human chimeric antigen receptor neutrophils, compositions, kits and methods of use | 普渡研究基金会 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | RAMP3 1335/4885CALCR 889/4885OPRM1 2070/4885 |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | RAMP3 1335/4885CALCR 889/4885OPRM1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.