Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212010 | 1.00 | GPR119 (0.56) | GPR119MMP13NR1H3NR1H2STS | |
| SCHEMBL21382279 | 0.91 | GPR119 (0.55) | GPR119NR1H3NR1H2STS | |
| SCHEMBL30567978 | 0.91 | GPR119 (0.55) | GPR119NR1H3NR1H2STS | |
| SCHEMBL23211967 | 0.91 | GPR119 (0.55) | GPR119NR1H3NR1H2STS | |
| SCHEMBL30330234 | 0.91 | GPR119 (0.55) | GPR119NR1H3NR1H2STS | |
| SCHEMBL21381945 | 0.86 | MGLL (0.40) | GPR119NR1H3NR1H2 | |
| SCHEMBL23211867 | 0.86 | MGLL (0.40) | GPR119NR1H3NR1H2 | |
| SCHEMBL22773313 | 0.83 | GPR119 (0.59) | GPR119MMP13 | |
| SCHEMBL22491546 | 0.83 | GPR119 (0.59) | GPR119MMP13 | |
| SCHEMBL22773261 | 0.79 | MMP13 (0.49) | GPR119MMP13STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |