Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23211806 | 1.00 | POLB (0.46) | POLBGPR119ALDH1A1KMT2AKDM4E | |
| SCHEMBL30149847 | 1.00 | POLB (0.46) | POLBGPR119ALDH1A1KMT2AKDM4E | |
| SCHEMBL29734416 | 0.88 | LMNA (0.50) | POLBGPR119ALDH1A1KMT2AMEN1 | |
| SCHEMBL22491440 | 0.88 | LMNA (0.50) | POLBGPR119ALDH1A1KMT2AMEN1 | |
| SCHEMBL23211976 | 0.87 | POLB (0.50) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL22491587 | 0.82 | PTAFR (0.51) | POLBGPR119ALDH1A1KMT2AKDM4E | |
| SCHEMBL29734522 | 0.82 | PTAFR (0.51) | POLBGPR119ALDH1A1KMT2AKDM4E | |
| SCHEMBL23212048 | 0.82 | GPR119 (0.49) | GPR119MAPK1CCNA2CDK2 | |
| SCHEMBL30568010 | 0.82 | GPR119 (0.49) | GPR119MAPK1CCNA2CDK2 | |
| SCHEMBL30149843 | 0.82 | GPR119 (0.49) | GPR119MAPK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |