Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149843 | 1.00 | GPR119 (0.49) | GPR119VNN1CCNA2CDK2GBA1 | |
| SCHEMBL23212048 | 1.00 | GPR119 (0.49) | GPR119VNN1CCNA2CDK2GBA1 | |
| SCHEMBL30567986 | 0.90 | GPR119 (0.51) | GPR119NR1H2NR1H3 | |
| SCHEMBL23211871 | 0.90 | GPR119 (0.51) | GPR119NR1H2NR1H3 | |
| SCHEMBL29734566 | 0.88 | GPR119 (0.54) | GPR119NR1H2NR1H3 | |
| SCHEMBL22491548 | 0.88 | GPR119 (0.54) | GPR119NR1H2NR1H3 | |
| SCHEMBL21381728 | 0.86 | VNN1 (0.46) | VNN1BRAFMAPK1 | |
| SCHEMBL23211806 | 0.82 | POLB (0.46) | GPR119CCNA2CDK2MAPK1 | |
| SCHEMBL30149847 | 0.82 | POLB (0.46) | GPR119CCNA2CDK2MAPK1 | |
| SCHEMBL30567965 | 0.82 | POLB (0.46) | GPR119CCNA2CDK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |