Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382064 | 1.00 | USP30 (0.42) | USP30RORCTACR1GPR119HDAC4 | |
| SCHEMBL23211885 | 0.88 | PDK2 (0.38) | RORCTACR1LIPE | |
| SCHEMBL30366151 | 0.84 | MEN1 (0.45) | USP30GPR119 | |
| SCHEMBL30899631 | 0.84 | MEN1 (0.45) | USP30GPR119 | |
| SCHEMBL21382137 | 0.84 | TRPV3 (0.47) | GPR119HPGDS | |
| SCHEMBL30568020 | 0.84 | TRPV3 (0.47) | GPR119HPGDS | |
| SCHEMBL5471664 | 0.77 | GPR119 (0.49) | GPR119HPGDSLIPE | |
| SCHEMBL21390304 | 0.75 | MGLL (0.51) | — | |
| SCHEMBL21390420 | 0.75 | MGLL (0.51) | — | |
| SCHEMBL23148883 | 0.75 | MGLL (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |