Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792428 | 1.00 | LPL (0.40) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL20203112 | 0.83 | LPL (0.34) | LPLLIPGEGFR | |
| SCHEMBL15393439 | 0.76 | LPL (0.41) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL17752336 | 0.74 | LPL (0.39) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL31378591 | 0.74 | LPL (0.39) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL22947113 | 0.73 | GSK3A (0.35) | LPLLIPG | |
| SCHEMBL21911080 | 0.72 | LPL (0.38) | LPLLIPGIDO1TDO2 | |
| SCHEMBL30508645 | 0.72 | LPL (0.38) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL15392968 | 0.72 | LPL (0.38) | LPLLIPGEGFRIDO1TDO2 | |
| SCHEMBL9977811 | 0.72 | LPL (0.33) | LPLLIPGIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472739-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |