SCHEMBL30568705

SCHEMBL30568705

O=[P@](CCc1ccccn1)(c1ccccc1)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
KCNA5 P22460 1/20 0.44
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 2/20 0.40
RECQL P46063 1/20 0.40
HRH3 Q9Y5N1 3/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HRH1 P35367 1/20 0.38
LMNA P02545 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31588355 0.80 RAB9A (0.44) ALDH1A1RAB9ASMN1; SMN2HRH3MEN1
SCHEMBL779718 0.75 ALDH1A1 (0.40) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL776467 0.73 NPSR1 (0.40) ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL11519007 0.70 CETP (0.42) ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL30568729 0.69 ALDH1A1 (0.51) ALDH1A1KCNA5SMN1; SMN2HRH3CYP1A2
SCHEMBL6850513 0.68 HPGD (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL777410 0.68 HTT (0.36) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL932969 0.68 FDPS (0.61) ALDH1A1KCNA5SMN1; SMN2HRH3CYP1A2
SCHEMBL4572677 0.66 HPGD (0.55) NPC1RAB9ASMN1; SMN2HPGDRECQL
SCHEMBL4572679 0.66 HPGD (0.55) NPC1RAB9ASMN1; SMN2HPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116731070-A Asymmetric catalytic synthesis method and application of chiral secondary phosphorus oxide and chiral aza-arene substituted tertiary phosphorus oxide 河南工业大学 2023-09-12 CN disclosed