Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332294 | 0.85 | RAB9A (0.59) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4466816 | 0.84 | CDK1 (0.66) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL28448931 | 0.82 | KDM4E (0.55) | HRH4KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL29883568 | 0.82 | HRH4 (0.62) | HRH4HRH3 | |
| SCHEMBL13811881 | 0.81 | PIM1 (0.65) | HRH4HRH3KDM4EMAPTALDH1A1 | |
| SCHEMBL3411485 | 0.80 | HRH4 (0.52) | HRH4HRH3KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4963320 | 0.78 | JAK2 (0.57) | HRH4HRH3KDM4EMAPTALDH1A1 | |
| SCHEMBL3417412 | 0.78 | KDM4E (0.53) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL265154 | 0.75 | DHFR (0.59) | HRH4KDM4EMAPTALDH1A1GAA | |
| SCHEMBL30560046 | 0.75 | DHFR (0.59) | HRH4KDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023179196-A1 | PREPARATION AND APPLICATION OF WEE1 KINASE INHIBITOR | 药雅科技(上海)有限公司 | 2023-09-28 | — | — | WO | disclosed |