Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28223160 | 0.75 | KDM4E (0.58) | KDM4EALDH1A1CYP11B1CYP11B2HSD11B1 | |
| SCHEMBL6313781 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1CYP11B1CYP11B2HSD11B1 | |
| SCHEMBL26831741 | 0.72 | LMNA (0.40) | MAOBMAOA | |
| SCHEMBL15870032 | 0.72 | LMNA (0.40) | MAOBMAOA | |
| SCHEMBL24247404 | 0.72 | LMNA (0.40) | MAOBMAOA | |
| SCHEMBL1769287 | 0.72 | — | — | |
| SCHEMBL6313788 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1CYP11B1CYP11B2HSD11B1 | |
| SCHEMBL24352139 | 0.71 | KDM4E (0.96) | KDM4EALDH1A1CYP11B1CYP11B2GRIN2D | |
| SCHEMBL6313783 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1CYP11B1CYP11B2HSD11B1 | |
| SCHEMBL2555430 | 0.66 | GRIN2D (0.46) | KDM4EALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151635-A1 | COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2023-08-17 | — | — | WO | disclosed |