Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.74 |
| ▸ | RGS12 | O14924 | 1/20 | 0.74 |
| ▸ | PMM2 | O15305 | 1/20 | 0.74 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYBB | P04839 | 1/20 | 0.74 |
| ▸ | BCHE | P06276 | 1/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354655 | 1.00 | METAP2 (0.74) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL4406056 | 0.85 | METAP2 (1.00) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL29370082 | 0.85 | METAP2 (1.00) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL33829 | 0.85 | METAP2 (1.00) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL19064566 | 0.84 | METAP2 (0.96) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL20678555 | 0.84 | METAP2 (0.96) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| Ebselen SCHEMBL20477111 | 0.84 | METAP2 (0.96) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| SCHEMBL193047 | 0.82 | METAP2 (0.79) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| SCHEMBL5916907 | 0.82 | METAP2 (0.68) | METAP2HDAC6KDM4EMEN1QSOX1 | |
| SCHEMBL28783439 | 0.81 | METAP2 (0.77) | METAP2HDAC6KDM4EMEN1QSOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110877-B | Benzisoselenazolone derivative, preparation method and application thereof in anti-coronavirus medicament | 青岛大学 | 2023-09-08 | — | — | CN | disclosed |