SCHEMBL29397226

SCHEMBL29397226

O=C(O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 6/20 0.44
▸ DPP8 Q6V1X1 2/20 0.44
▸ FAP Q12884 1/20 0.44
▸ DPP9 Q86TI2 1/20 0.44
▸ DPP7 Q9UHL4 1/20 0.44
▸ CAPN1 P07384 4/20 0.41
▸ CTSB P07858 1/20 0.41
▸ ANPEP P15144 1/20 0.38
▸ GRB2 P62993 1/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ITGB1 P05556 1/20 0.36
▸ ITGA4 P13612 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397117 0.98 DPP4 (0.46) DPP4DPP8FAPDPP9DPP7
SCHEMBL29658175 0.90 CAPN1 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL29616517 0.90 CAPN1 (0.51) DPP4DPP8FAPDPP9DPP7
SCHEMBL29765255 0.89 CAPN1 (0.47) DPP4DPP8FAPDPP9DPP7
SCHEMBL30574235 0.88 DPP4 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL2184762 0.87 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL29408003 0.87 DPP4 (0.45) DPP4DPP8FAPDPP9DPP7
SCHEMBL2194423 0.87 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL21519838 0.87 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL30445980 0.86 CAPN1 (0.41) DPP7CAPN1CTSBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055154-A1 LONG-ACTING DUAL-AGONIST COMPOUND CHENGDU AODA BIOTECHNOLOGY CO LTD (CN) 2026-02-26 — — US claimed
WO-2025087344-A1 GLP1-R/GIPR DUAL PEPTIDE AGONISTS AND USE THEREOF BETA PHARMA, INC. (US) 2025-05-01 — — WO claimed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 — — EP claimed
WO-2023031455-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS SANOFI SA (FR) 2023-03-09 — — WO claimed
WO-2022156189-A1 USE OF POLYPEPTIDE COMPOUND IN PREVENTION OR TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INTESTINAL FIBROSIS RELATED THERETO 深圳市图微安创科技开发有限公司 2022-07-28 — — WO claimed
CN-114478744-A Long-acting GLP-1 antagonist 成都奥达生物科技有限公司 2022-05-13 — — CN claimed
US-20260055154-A1 LONG-ACTING DUAL-AGONIST COMPOUND CHENGDU AODA BIOTECHNOLOGY CO LTD (CN) 2026-02-26 — — US disclosed
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
WO-2025264785-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
WO-2025087344-A1 GLP1-R/GIPR DUAL PEPTIDE AGONISTS AND USE THEREOF BETA PHARMA, INC. (US) 2025-05-01 — — WO disclosed
CN-118791589-A Polypeptide synthesis method with long chain side chain 甘肃瑞德林生物有限公司 2024-10-18 — — CN disclosed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 — — EP disclosed
EP-4196495-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP Pharma GmbH (CH) 2023-06-21 — — EP disclosed
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications SHENZHEN TURIER BIOTECH CO., LTD (CN) 2023-06-15 — — US disclosed
WO-2023031455-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS SANOFI SA (FR) 2023-03-09 — — WO disclosed
CN-115768460-A Long-acting GLP-1/GIP dual agonists 太阳医药工业有限公司 2023-03-07 — — CN disclosed
WO-2022156189-A1 USE OF POLYPEPTIDE COMPOUND IN PREVENTION OR TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INTESTINAL FIBROSIS RELATED THERETO 深圳市图微安创科技开发有限公司 2022-07-28 — — WO disclosed
WO-2022156189-A1 USE OF POLYPEPTIDE COMPOUND IN PREVENTION OR TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INTESTINAL FIBROSIS RELATED THERETO 深圳市图微安创科技开发有限公司 2022-07-28 — — WO disclosed
CN-114478744-A Long-acting GLP-1 antagonist 成都奥达生物科技有限公司 2022-05-13 — — CN disclosed
WO-2022034062-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP PHARMA AG (CH) 2022-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications IAPP, PNLIP, DPP4 DPP4 3/4885DPP8 13/4885FAP 99/4885
US-20260055154-A1 LONG-ACTING DUAL-AGONIST COMPOUND GIPR, GLP1R, GCG DPP4 81/4885DPP8 303/4885FAP 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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