Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576056 | 0.89 | F2 (0.49) | NPC1RAB9ATP53PKMKMT2A | |
| SCHEMBL30576091 | 0.87 | BRAF (0.53) | NPC1RAB9AKMT2AHTR1AHTR1F | |
| SCHEMBL30576064 | 0.83 | ITGB2 (0.49) | PKMKMT2AMEN1CDK2CCNA1 | |
| SCHEMBL30576180 | 0.83 | POLB (0.47) | NPC1RAB9APKMHTR1FSMN1; SMN2 | |
| SCHEMBL30576069 | 0.82 | NPC1 (0.57) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL30576128 | 0.81 | MAPT (0.55) | NPC1RAB9ATP53PKMKMT2A | |
| SCHEMBL30576104 | 0.80 | DYRK1A (0.54) | NPC1RAB9ATP53PKMKMT2A | |
| SCHEMBL30576073 | 0.80 | RAB9A (0.56) | RAB9APRKCIMAPTHTR1AHTR1F | |
| SCHEMBL30576093 | 0.80 | RXRA (0.46) | MAPTDYRK1AMAPK14 | |
| SCHEMBL29083767 | 0.79 | RXRA (0.58) | NPC1RAB9ATP53PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |