Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | WNT1 | P04628 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576056 | 0.91 | F2 (0.49) | DYRK1AGSK3BF2MAPK14MAPK13 | |
| SCHEMBL30576128 | 0.91 | MAPT (0.55) | DYRK1AGSK3BF2MAPK14MAPK13 | |
| SCHEMBL29083767 | 0.88 | RXRA (0.58) | DYRK1AGSK3BF2MAPK14MAPK13 | |
| SCHEMBL30576105 | 0.87 | DYRK1A (0.60) | DYRK1AGSK3BWNT1F2MAPK14 | |
| SCHEMBL30576143 | 0.84 | DYRK1A (0.54) | DYRK1AGSK3BWNT1F2MAPK14 | |
| SCHEMBL30576175 | 0.84 | CHRM1 (0.55) | DYRK1AGSK3BWNT1F2MAPK14 | |
| SCHEMBL30576069 | 0.81 | NPC1 (0.57) | DYRK1AGSK3BWNT1NPC1RAB9A | |
| SCHEMBL30576138 | 0.80 | NPC1 (0.51) | DYRK1AMAPK14NPC1RAB9AMEN1 | |
| SCHEMBL30576121 | 0.80 | MAPK14 (0.52) | DYRK1AGSK3BWNT1MAPK14NPC1 | |
| SCHEMBL30576180 | 0.80 | POLB (0.47) | DYRK1AGSK3BWNT1MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |