Sugi Predict

Sugi Predict / Compounds / SCHEMBL30577488

SCHEMBL30577488

SCHEMBL30577488

O=c1[nH]c2ccccc2c2cc[nH]c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.59
▸ ALDH1A1 P00352 4/20 0.59
▸ PARP1 P09874 4/20 0.59
▸ GPR3 P46089 2/20 0.59
▸ HSD17B10 Q99714 2/20 0.59
▸ LMNA P02545 2/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ TNKS O95271 1/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ BLM P54132 1/20 0.59
▸ PMP22 Q01453 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ PARP15 Q460N3 1/20 0.59
▸ TNKS2 Q9H2K2 1/20 0.59
▸ MAPT P10636 1/20 0.48
▸ IDE P14735 1/20 0.48
▸ MPI P34949 1/20 0.48
▸ CACNA1B Q00975 1/20 0.48
▸ APBA1 Q02410 1/20 0.48
▸ CA12 O43570 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552450 1.00 KDM4E (0.59) KDM4EALDH1A1PARP1GPR3HSD17B10
SCHEMBL13738861 0.86 PARP1 (0.61) KDM4EALDH1A1PARP1GPR3HSD17B10
SCHEMBL30577482 0.86 PARP1 (0.61) KDM4EALDH1A1PARP1GPR3HSD17B10
Propionic Acid SCHEMBL4171576 0.86 PIM1 (0.46) KDM4EALDH1A1PARP1GPR3HSD17B10
SCHEMBL21384427 0.85 ALDH1A1 (0.53) KDM4EALDH1A1PARP1GPR3HSD17B10
Butyric Acid SCHEMBL4162573 0.84 KDM4E (0.46) KDM4EALDH1A1PARP1GPR3HSD17B10
SCHEMBL4160378 0.82 NPC1 (0.42) KDM4EALDH1A1PARP1GPR3HSD17B10
3-Methylbutanoic Acid SCHEMBL4162528 0.82 PIM1 (0.43) KDM4EALDH1A1PARP1GPR3HSD17B10
SCHEMBL19683290 0.76 PARP1 (0.44) KDM4EALDH1A1PARP1HSD17B10LMNA
SCHEMBL4716605 0.75 PARP1 (0.42) KDM4EALDH1A1PARP1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591596-A 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-03-11 — — CN claimed
EP-4490161-A1 SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF Impact Therapeutics (Shanghai), Inc. (CN) 2025-01-15 — — EP claimed
CN-119013279-A Substituted tricyclic compounds as PARP inhibitors and uses thereof 上海瑛派药业有限公司 2024-11-22 — — CN claimed
WO-2023169226-A1 SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF Impact Therapeutics (Shanghai), Inc (CN) 2023-09-14 — — WO claimed
CN-119591596-B 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-10-17 — — CN disclosed
CN-119591596-A 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-03-11 — — CN disclosed
CN-119591596-A 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-03-11 — — CN disclosed
CN-119591596-A 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-03-11 — — CN disclosed
EP-4490161-A1 SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF Impact Therapeutics (Shanghai), Inc. (CN) 2025-01-15 — — EP disclosed
CN-119013279-A Substituted tricyclic compounds as PARP inhibitors and uses thereof 上海瑛派药业有限公司 2024-11-22 — — CN disclosed
WO-2023169226-A1 SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF Impact Therapeutics (Shanghai), Inc (CN) 2023-09-14 — — WO disclosed