Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728025 | 0.88 | LMNA (0.42) | LMNASTING1ALDH1A1KDM4ENPC1 | |
| SCHEMBL30579393 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EKMT2APOLBIRAK4 | |
| SCHEMBL30579391 | 0.79 | IRAK4 (0.41) | KDM4ENPC1RAB9AIRAK4 | |
| SCHEMBL19045790 | 0.75 | PDE2A (0.57) | LMNAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL19030768 | 0.75 | LMNA (0.72) | LMNASTING1ALDH1A1KDM4ENPC1 | |
| SCHEMBL19029939 | 0.74 | LMNA (0.47) | LMNASTING1ALDH1A1KDM4ENPC1 | |
| SCHEMBL10071025 | 0.74 | LMNA (0.44) | LMNASTING1ALDH1A1KDM4ENPC1 | |
| SCHEMBL29728005 | 0.72 | KDM4E (0.49) | LMNAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL19029896 | 0.72 | PDE2A (0.45) | LMNAALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL30579412 | 0.70 | KDM4E (0.43) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |