Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728025 | 0.84 | LMNA (0.42) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29728006 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1HPGDPOLBHTT | |
| SCHEMBL29727997 | 0.75 | IRAK4 (0.41) | KDM4EALDH1A1HPGDMAP2K1HTT | |
| SCHEMBL16718858 | 0.74 | HSD17B10 (0.67) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL17781274 | 0.72 | KDM4E (0.57) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL30579399 | 0.72 | LMNA (0.45) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23728550 | 0.71 | ALDH1A1 (0.56) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL23728526 | 0.71 | ALDH1A1 (0.56) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL6633145 | 0.71 | KDM4E (0.55) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL25879499 | 0.71 | EGFR (0.47) | KDM4ENPC1RAB9ACSNK1DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114667287-A | Adenosine A2A receptor antagonists and uses thereof | 泰昂治疗公司 | 2022-06-24 | — | — | CN | disclosed |