Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16622507 | 1.00 | EPHX1 (0.42) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL305547 | 0.98 | EPHX1 (0.39) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL9669443 | 0.94 | EPHX1 (0.35) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL305167 | 0.85 | EPHX1 (0.40) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| Cilexetil SCHEMBL3483374 | 0.84 | EPHX1 (0.44) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL16731836 | 0.84 | EPHX1 (0.44) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL12603500 | 0.84 | EPHX1 (0.42) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL1240114 | 0.82 | EPHX1 (0.43) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL1240113 | 0.82 | EPHX1 (0.43) | EPHX1CYP19A1NAAAHTTCYP2C19 | |
| SCHEMBL3483069 | 0.82 | EPHX1 (0.41) | EPHX1CYP19A1NAAAHTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440570-B | Preparation method of ceftiofur ester compound or halogen salt thereof | 济宁市化工研究院 | 2020-12-04 | — | — | CN | claimed |
| US-7153972-B2 | Benzimidazole derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2006-12-26 | — | — | US | claimed |
| US-20050131039-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2005-06-16 | — | — | US | claimed |
| US-6844443-B2 | Benzimidazole derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LTD. (JP) | 2005-01-18 | — | — | US | claimed |
| US-20040044223-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2004-03-04 | — | — | US | claimed |
| US-20020151723-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2002-10-17 | — | — | US | claimed |
| US-4935508-A | Acylation of 7-aminocephalosporin with alkyl 2-(2-amino-thiazol-4-yl)-2-oximinoacetate | BRISTOL-MYERS COMPANY (US) | 1990-06-19 | — | — | US | claimed |
| JP-60218394-A | — | — | None | — | — | JP | disclosed |
| US-20230000812-A1 | IBUPROFEN ESTER PRODRUG, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND APPLICATION | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
| US-20220274911-A1 | ARYLPROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND APPLICATION THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2022-09-01 | — | — | US | disclosed |
| CN-114746394-A | Aryl propionic acid derivative, pharmaceutical composition, preparation method and application thereof | 南京海融医药科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114728883-A | Ibuprofen ester prodrug, pharmaceutical composition, preparation method and application | 南京海融医药科技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-4001258-A1 | ARYL PROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF | Nanjing Heron Pharmaceutical Science and Technology Co., Ltd. (CN) | 2022-05-25 | — | — | EP | disclosed |
| EP-0304036-A2 | 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof | Bristol-Myers Squibb Company (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0128029-B1 | CEPHALOSPORIN ESTER DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0250143-A1 | Isoxazolidinone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| US-4616008-A | LIPID-SOLUBLE CEPHALOSPORINS AND CYCLODEXTRINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0163433-A2 | Antibacterial solid composition for oral administation | Takeda Chemical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |
| JP-S60218394-A | CEPHALOSPORIN ESTER DERIVATIVE | TAKEDA CHEM IND LTD | 1985-11-01 | — | — | JP | disclosed |
| EP-0128029-A2 | Cephalosporin ester derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000812-A1 | IBUPROFEN ESTER PRODRUG, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND APPLICATION | PTGER1, CYP4A11, FABP4 | EPHX1 199/4885CYP19A1 19/4885NAAA 623/4885 |
| US-20050131039-A1 | Benzimidazole derivatives, their production and use | MRM1, CARM1, H1-4 | EPHX1 3533/4885CYP19A1 1450/4885NAAA 2315/4885 |
| US-20040044223-A1 | Benzimidazole derivatives, their production and use | HAT1, MRM1, H1-4 | EPHX1 3612/4885CYP19A1 1315/4885NAAA 2213/4885 |
| US-20020151723-A1 | Benzimidazole derivatives, their production and use | HAT1, MRM1, NSD1 | EPHX1 3633/4885CYP19A1 1445/4885NAAA 2468/4885 |
| US-20220274911-A1 | ARYLPROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND APPLICATION THEREOF | CYP2A7, CYP2A6, CYP3A7 | EPHX1 952/4885CYP19A1 128/4885NAAA 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.