Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760910 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5899720 | 0.86 | CA2 (0.47) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29424578 | 0.86 | CA2 (0.47) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4785145 | 0.85 | SNCA (0.38) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3716907 | 0.84 | LMNA (0.39) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3917846 | 0.84 | LMNA (0.42) | CA9CA12ALDH1A1MAPTMEN1 | |
| SCHEMBL15454943 | 0.83 | ACHE (0.47) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL16290424 | 0.83 | SNCA (0.42) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18117618 | 0.81 | SNCA (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17148312 | 0.81 | EGFR (0.40) | ALDH1A1MAPTMEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813526-A | Isoindolinone compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-09-29 | — | — | CN | disclosed |