Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038744 | 0.79 | CYP3A4 (0.40) | CYP3A4MAPTALDH1A1ENPP2ORAI1 | |
| SCHEMBL5206042 | 0.79 | CA12 (0.35) | CYP3A4MAPTALDH1A1ENPP2ORAI1 | |
| SCHEMBL7631870 | 0.78 | HSD17B10 (0.32) | — | |
| SCHEMBL27988498 | 0.77 | ACHE (0.46) | CYP3A4MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL30583101 | 0.75 | GAA (0.36) | CYP3A4MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL30567519 | 0.75 | ALDH1A1 (0.44) | CYP3A4MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL30544154 | 0.75 | HTR2A (0.36) | MAPTALDH1A1TDP1ENPP2ORAI1 | |
| SCHEMBL7629905 | 0.74 | HSD17B10 (0.31) | — | |
| SCHEMBL31598610 | 0.73 | TUBB1 (0.36) | MAPTALDH1A1TDP1ENPP2ORAI1 | |
| SCHEMBL4858235 | 0.73 | CA1 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813526-A | Isoindolinone compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-09-29 | — | — | CN | disclosed |