SCHEMBL4858235

SCHEMBL4858235

OB(O)Oc1c(F)c(F)cc(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA4 P22748 2/20 0.34
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
MAPT P10636 1/20 0.32
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL30084364 0.98 CA1 (0.33) CA1CA2CA4CES2CES1
SCHEMBL3671745 0.86 CA1 (0.32) CA1CA2CA4CES2CES1
SCHEMBL29396896 0.86 CA1 (0.32) CA1CA2CA4CES2CES1
SCHEMBL8156122 0.85
Benzene SCHEMBL29853972 0.82 CA1 (0.30) CA1CA2CA4
SCHEMBL7626884 0.81
SCHEMBL1483899 0.79 CA1 (0.32) CA1CA2CA4CES2CES1
SCHEMBL28407176 0.79
Trimethylammonium SCHEMBL28070834 0.79
SCHEMBL166503 0.78 CA1 (0.31) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985463-B Bridged metallocene compound catalyst, preparation method and application thereof 中国石油天然气股份有限公司 2018-04-03 CN claimed
CN-106699949-A Ethylene-alpha olefin-non-conjugated diene polymer and preparation method thereof 中国石油化工股份有限公司 2017-05-24 CN claimed
CN-104448062-B Preparation method of metallocene catalyst 中国石油天然气股份有限公司 2017-02-15 CN claimed
CN-106366226-A Transition metal catalyst composition and applications thereof 中国石油化工股份有限公司 2017-02-01 CN claimed
CN-105985463-A Bridged metallocene compound catalyst, preparation method and application thereof 中国石油天然气股份有限公司 2016-10-05 CN claimed
CN-105985384-A Dinuclear metallocene compound, preparation method and application thereof 中国石油天然气股份有限公司 2016-10-05 CN claimed
CN-104448062-A Preparation method of metallocene catalyst PETROCHINA CO LTD 2015-03-25 CN claimed
CN-104159929-A Supported composite metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same SK INNOVATION CO LTD 2014-11-19 CN claimed
CN-1178949-C Cyclopentadienyl transition metal compounds, as polymerization catalysts �Ϻ���ͨ��ѧ 2004-12-08 CN claimed
CN-1302303-A Cyclopentadienyl transition metal compounds, as polymerization catalysts EASTMAN CHEM CO (US) 2001-07-04 CN claimed
US-12637524-B2 Polymerization catalyst having a tetradentate ligand NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2026-05-26 US disclosed
CN-117402275-B Metallocene catalyst and preparation method thereof 中国石油天然气股份有限公司 2026-05-15 CN disclosed
US-20260103484-A1 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD FOR PREPARING OLEFIN POLYMER USING THE SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2026-04-16 US disclosed
US-12486342-B2 Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2025-12-02 US disclosed
EP-4139320-B1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS INTERNATIONAL SA (CH) 2025-08-20 EP disclosed
CN-1194650-A Transition metal complexes, catalyst for olefin polymerization, and process for producing olefin polymers SUMITOMO CHEMICAL CO (JP) 1998-09-30 CN disclosed
CN-1193323-A Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 1998-09-16 CN disclosed
CN-1185447-A Propene-1-butene copolymer SUMITOMO CHEMICAL CO (JP) 1998-06-24 CN disclosed
CN-1151409-A Olefin polymerizationc atalyst component, olefin polymerizationc atalyst and producing olefin polymer SUMITOMO CHEMICAL CO (JP) 1997-06-11 CN disclosed
CN-1145370-A Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL CO (JP) 1997-03-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486342-B2 Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes HCFC1, AP1M1, AP3M1 CA1 431/4885CA2 2984/4885CA4 1885/4885
US-12637524-B2 Polymerization catalyst having a tetradentate ligand HAO2, POF1B, DUOX2 CA1 1542/4885CA2 2537/4885CA4 974/4885
US-20260103484-A1 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD FOR PREPARING OLEFIN POLYMER USING THE SAME MMP20, CYC1, SOD1 CA1 141/4885CA2 268/4885CA4 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.