Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.54 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.49 |
| ▸ | CALCR | P30988 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584470 | 0.88 | EPHA2 (0.56) | OPRM1OPRD1CALCR | |
| SCHEMBL30584461 | 0.87 | CALCRL (0.51) | CALCRLRAMP1RENAGTR2AGTR1 | |
| SCHEMBL29994173 | 0.84 | CALCRL (0.59) | CALCRLRAMP1RENAGTR2AGTR1 | |
| SCHEMBL31020743 | 0.84 | NTSR1 (0.52) | AGTR2AGTR1SLC6A2NTSR2NTSR1 | |
| SCHEMBL30584443 | 0.84 | SLC6A2 (0.55) | RENAGTR2AGTR1SLC6A2NTSR2 | |
| SCHEMBL6887928 | 0.82 | OPRD1 (0.55) | OPRM1OPRD1NTSR1 | |
| SCHEMBL6887945 | 0.82 | OPRD1 (0.55) | OPRM1OPRD1NTSR1 | |
| SCHEMBL11157501 | 0.82 | SLC6A2 (0.58) | RENSLC6A2OPRM1OPRD1NTSR2 | |
| SCHEMBL11157497 | 0.82 | SLC6A2 (0.58) | RENSLC6A2OPRM1OPRD1NTSR2 | |
| SCHEMBL6515614 | 0.82 | SLC6A2 (0.69) | CALCRLRENSLC6A2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212662-A2 | COMPOSITIONS AND METHODS FOR MODULATING ANTIGEN BINDING ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-11-02 | — | — | WO | disclosed |