Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 14/20 | 0.52 |
| ▸ | NTSR2 | O95665 | 12/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 10/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584476 | 0.84 | CALCRL (0.54) | NTSR1NTSR2SLC6A2SORT1AGTR2 | |
| SCHEMBL31717953 | 0.82 | NTSR1 (0.56) | NTSR1NTSR2SLC6A2SORT1 | |
| SCHEMBL31694383 | 0.81 | NTSR1 (0.68) | NTSR1NTSR2SLC6A2SORT1 | |
| SCHEMBL30584461 | 0.80 | CALCRL (0.51) | SLC6A2AGTR2AGTR1 | |
| SCHEMBL30102048 | 0.79 | OPRD1 (0.52) | NTSR1NTSR2SLC6A2 | |
| SCHEMBL31356485 | 0.79 | ANPEP (0.64) | NTSR1NTSR2SLC6A2SORT1ANPEP | |
| SCHEMBL29722981 | 0.79 | CXCL8 (0.50) | NTSR1NTSR2SORT1 | |
| SCHEMBL31362677 | 0.79 | OPRM1 (0.57) | NTSR1NTSR2SLC6A2SORT1ANPEP | |
| SCHEMBL31362645 | 0.78 | LNPEP (0.59) | NTSR1NTSR2SLC6A2AGTR2AGTR1 | |
| SCHEMBL30584443 | 0.78 | SLC6A2 (0.55) | NTSR1NTSR2SLC6A2SORT1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847223-B2 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20250002584-A1 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-01-02 | — | — | US | disclosed |
| US-12065492-B2 | Anti-B7-H6 antibody, fusion proteins, and methods of using the same | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2024-08-20 | — | — | US | disclosed |
| CN-110511278-B | Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof | 达特茅斯大学理事会 | 2024-08-09 | — | — | CN | disclosed |