SCHEMBL30584727

SCHEMBL30584727

O=C(NCCCN1CCC(Cc2ccccn2)CC1)N1CCN(c2nc(-c3ccc(C(F)(F)F)cc3)no2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ PKM P14618 1/20 0.47
▸ CCR3 P51677 2/20 0.45
▸ CHRM2 P08172 3/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ TP53 P04637 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ TSHR P16473 1/20 0.45
▸ CHRM1 P11229 2/20 0.44
▸ SRPK1 Q96SB4 1/20 0.43
▸ DRD2 P14416 4/20 0.43
▸ DRD3 P35462 4/20 0.43
▸ GSK3B P49841 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ CHRM4 P08173 2/20 0.42
▸ MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584882 0.92 LMNA (0.46) LMNAKMT2ACCR3ALDH1A1TP53
SCHEMBL30584805 0.91 LMNA (0.48) LMNAKMT2ACHRM2ALDH1A1TP53
SCHEMBL31546341 0.90 EPHX2 (0.49) LMNAKMT2AALDH1A1TP53HTT
SCHEMBL30584895 0.90 LMNA (0.45) LMNAKMT2AALDH1A1TP53HTT
SCHEMBL31667543 0.88 LMNA (0.58) LMNAKMT2AALDH1A1TP53HTT
SCHEMBL31546447 0.88 CCR3 (0.46) LMNAKMT2ACCR3ALDH1A1TP53
SCHEMBL30584775 0.88 LMNA (0.49) LMNAKMT2AALDH1A1TP53HTT
Formic Acid SCHEMBL31546410 0.86 LMNA (0.56) LMNAKMT2AALDH1A1TP53HTT
SCHEMBL25434754 0.81 MEN1 (0.56) LMNAKMT2ACHRM2ALDH1A1TP53
SCHEMBL31667422 0.80 LMNA (0.45) LMNAKMT2ACHRM2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 LMNA 1344/4885KMT2A 1404/4885PKM 2527/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1344/4885KMT2A 1404/4885PKM 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback