SCHEMBL31667543

SCHEMBL31667543

COc1ccc(-c2noc(N3CCN(C(=O)NCCCN4CCC(Cc5ccccn5)CC4)CC3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.58
▸ TP53 P04637 5/20 0.58
▸ HTT P42858 4/20 0.58
▸ SMN1; SMN2 Q16637 4/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ TSHR P16473 2/20 0.58
▸ MAPT P10636 6/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ MEN1 O00255 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ NPC1 O15118 1/20 0.50
▸ GAA P10253 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL31546410 0.97 LMNA (0.56) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL30584775 0.91 LMNA (0.49) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL30584805 0.91 LMNA (0.48) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL31546341 0.90 EPHX2 (0.49) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL30584882 0.90 LMNA (0.46) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL31667398 0.90 LMNA (0.55) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL31546418 0.90 LMNA (0.72) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL30584727 0.88 LMNA (0.47) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL31546447 0.88 CCR3 (0.46) LMNATP53HTTSMN1; SMN2ALDH1A1
SCHEMBL30584895 0.88 LMNA (0.45) LMNATP53HTTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
Send feedback