SCHEMBL31667422

SCHEMBL31667422

O=C(NCOCN1CCC(Cc2ccccn2)CC1)N1CCN(c2nc(-c3ccc(OC(F)(F)F)cc3)no2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.45
▸ MAPT P10636 5/20 0.45
▸ TP53 P04637 4/20 0.45
▸ HTT P42858 3/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ CHRM4 P08173 3/20 0.43
▸ THRB P10828 1/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ TSHR P16473 1/20 0.38
▸ EPHX2 P34913 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ DPP4 P27487 1/20 0.38
▸ DPP7 Q9UHL4 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584805 0.90 LMNA (0.48) LMNAMAPTTP53HTTALDH1A1
SCHEMBL31546384 0.88 LMNA (0.44) LMNAMAPTTP53HTTALDH1A1
SCHEMBL31667518 0.88 MAPT (0.45) LMNAMAPTTP53HTTALDH1A1
SCHEMBL25434754 0.82 MEN1 (0.56) LMNAMAPTTP53HTTALDH1A1
SCHEMBL30584727 0.80 LMNA (0.47) LMNAMAPTTP53HTTALDH1A1
SCHEMBL31667543 0.80 LMNA (0.58) LMNAMAPTTP53HTTALDH1A1
SCHEMBL30584775 0.80 LMNA (0.49) LMNAMAPTTP53HTTALDH1A1
SCHEMBL30584882 0.79 LMNA (0.46) LMNAMAPTTP53HTTALDH1A1
Formic Acid SCHEMBL31546410 0.78 LMNA (0.56) LMNAMAPTTP53HTTALDH1A1
SCHEMBL31546341 0.78 EPHX2 (0.49) LMNAMAPTTP53HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
Send feedback