SCHEMBL30584743

SCHEMBL30584743

COc1cnc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccc(C)cc5)C4)CC3)n2)nc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 1/20 0.51
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ CHRM4 P08173 2/20 0.47
▸ LMNA P02545 2/20 0.47
▸ TP53 P04637 3/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584783 0.92 CCR5 (0.53) CCR5MEN1KMT2ACHRM4LMNA
SCHEMBL25433890 0.92 CCR5 (0.53) CCR5MEN1KMT2ACHRM4LMNA
SCHEMBL25437981 0.90 LMNA (0.59) CCR5MEN1KMT2ALMNASMN1; SMN2
SCHEMBL31546339 0.89 CCR5 (0.50) CCR5MEN1KMT2ALMNATP53
SCHEMBL25433652 0.87 CCR5 (0.51) CCR5MEN1KMT2ACHRM4LMNA
SCHEMBL25439449 0.87 CCR5 (0.49) CCR5MEN1KMT2ALMNASMN1; SMN2
SCHEMBL25439353 0.87 MEN1 (0.53) CCR5MEN1KMT2ACHRM4LMNA
SCHEMBL30584865 0.87 MEN1 (0.53) CCR5MEN1KMT2ACHRM4LMNA
SCHEMBL31667355 0.85 LMNA (0.58) MEN1KMT2ALMNATP53SMN1; SMN2
SCHEMBL30584799 0.85 CCR5 (0.52) CCR5CHRM4LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 CCR5 3713/4885MEN1 1569/4885KMT2A 1404/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CCR5 3713/4885MEN1 1569/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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