Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA7 | P43166 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047860 | 0.86 | CA12 (0.56) | CA12CA1CA7CA9CA13 | |
| SCHEMBL434686 | 0.78 | CYP3A4 (0.80) | CA12CA1CA7CA9CA13 | |
| SCHEMBL6361059 | 0.78 | CYP3A4 (0.75) | CA12CA1CA7CA9CA13 | |
| SCHEMBL31542614 | 0.78 | CYP3A4 (0.80) | CA12CA1CA7CA9CA13 | |
| SCHEMBL3273868 | 0.74 | KDM4E (0.54) | CA12CA1CA7CA9CA13 | |
| SCHEMBL17047859 | 0.74 | ALDH1A1 (0.70) | CA12CA1CA7CA9CA13 | |
| SCHEMBL30498930 | 0.73 | ALDH1A1 (0.55) | CA12CA1CA7CA9CA13 | |
| SCHEMBL14667069 | 0.73 | CA9 (0.50) | CA12CA1CA7CA9CA13 | |
| SCHEMBL30303166 | 0.72 | CA9 (0.60) | CA12CA1CA7CA9CA13 | |
| SCHEMBL4659463 | 0.71 | CA9 (0.77) | CA12CA1CA7CA9CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479540-A1 | COUMARIN SYNTHESIS AND USES THEREOF | BASF SE (DE) | 2024-12-25 | — | — | EP | claimed |
| CN-118715324-A | Coumarin synthesis and application thereof | 巴斯夫欧洲公司 | 2024-09-27 | — | — | CN | claimed |
| WO-2023156270-A1 | COUMARIN SYNTHESIS AND USES THEREOF | BASF SE (DE) | 2023-08-24 | — | — | WO | claimed |
| EP-4479540-A1 | COUMARIN SYNTHESIS AND USES THEREOF | BASF SE (DE) | 2024-12-25 | — | — | EP | disclosed |
| CN-118715324-A | Coumarin synthesis and application thereof | 巴斯夫欧洲公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2023156270-A1 | COUMARIN SYNTHESIS AND USES THEREOF | BASF SE (DE) | 2023-08-24 | — | — | WO | disclosed |