Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DTYMK | P23919 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688017 | 0.77 | ALDH1A1 (0.39) | TDP1L3MBTL1TSHRPOLBTXNRD1 | |
| SCHEMBL27253953 | 0.76 | CA12 (0.39) | CA1CA2CTNNB1WNT3A | |
| SCHEMBL22208655 | 0.76 | CA1 (0.39) | TDP1L3MBTL1CASP6TSHRCA1 | |
| SCHEMBL13091643 | 0.75 | CTNNB1 (0.37) | CTNNB1WNT3A | |
| SCHEMBL22208517 | 0.75 | CTNNB1 (0.37) | CTNNB1WNT3A | |
| SCHEMBL8975989 | 0.73 | TDP1 (0.42) | TDP1TSHRCA1CA2TXNRD1 | |
| SCHEMBL3826317 | 0.73 | TDP1 (0.62) | TDP1L3MBTL1CASP6TSHRCA1 | |
| SCHEMBL10749290 | 0.73 | TXNRD1 (0.62) | TDP1L3MBTL1CASP6POLBPKM | |
| SCHEMBL11262989 | 0.73 | TXNRD1 (0.46) | TDP1L3MBTL1CASP6POLBPKM | |
| SCHEMBL31726102 | 0.71 | DTYMK (0.44) | TDP1CASP6TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| EP-2167484-B1 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| EP-2167484-B1 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2167484-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009010260-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009010260-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273830-A1 | NOVEL INSECTICIDES | NR5A2, NR2C2, NOX5 | TDP1 4302/4885L3MBTL1 1257/4885CASP6 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.