Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063401 | 0.86 | KMO (0.31) | LDHAMAPT | |
| SCHEMBL3786837 | 0.83 | NOTUM (0.36) | NOTUMLDHACFTRALDH1A1HSD17B10 | |
| SCHEMBL1583640 | 0.82 | NOTUM (0.41) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL1583465 | 0.81 | NOTUM (0.42) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL1583159 | 0.81 | NOTUM (0.40) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL3691065 | 0.81 | CFTR (0.40) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL1584276 | 0.81 | NOTUM (0.38) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL3793277 | 0.80 | NOTUM (0.41) | NOTUMLDHAMRGPRX4CFTRALDH1A1 | |
| SCHEMBL3689642 | 0.80 | NOTUM (0.36) | NOTUMCFTRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3786834 | 0.79 | NOTUM (0.36) | NOTUMLDHACFTRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | BASKARAN SUBRAMANIAN | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | ZC3HAV1, MAVS, EIF2AK2 | NOTUM 3110/4885LDHA 3993/4885MRGPRX4 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.