Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086059 | 1.00 | IKBKB (0.48) | IKBKBCHUKHDAC8NAPRTHTR1A | |
| Hydrochloric Acid SCHEMBL21640226 | 0.98 | IKBKB (0.47) | IKBKBCHUKHDAC8NAPRTHTR1A | |
| SCHEMBL13188191 | 0.86 | PRKCZ (0.45) | IKBKBHDAC8HTR1AHTR7NAMPT | |
| SCHEMBL4502706 | 0.86 | KDM4E (0.48) | HDAC8NAPRTHTR1AHTR7NAMPT | |
| SCHEMBL4502704 | 0.86 | KDM4E (0.48) | HDAC8NAPRTHTR1AHTR7NAMPT | |
| SCHEMBL1282031 | 0.85 | HDAC8 (0.56) | HDAC8NAPRTHTR1AHTR7RORC | |
| SCHEMBL783637 | 0.83 | SMN1; SMN2 (0.56) | HDAC8HTR1AHTR7RORCDRD2 | |
| SCHEMBL15225912 | 0.81 | SMN1; SMN2 (0.59) | HDAC8HTR1AHTR7NAMPTALDH1A1 | |
| SCHEMBL27552611 | 0.80 | KDM4E (0.50) | IKBKBCHUKHTR1AHTR7ALDH1A1 | |
| SCHEMBL578884 | 0.79 | RORC (0.46) | HDAC8NAPRTHTR1AHTR7RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |