Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783637 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ERECQLALDH1A1NAMPT | |
| Bicarbonate SCHEMBL15226047 | 0.94 | NAMPT (0.57) | SMN1; SMN2KDM4ERECQLALDH1A1NAMPT | |
| SCHEMBL1282031 | 0.92 | HDAC8 (0.56) | SMN1; SMN2KDM4ERECQLALDH1A1NAMPT | |
| SCHEMBL21959842 | 0.86 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TSHRHTTHDAC8 | |
| SCHEMBL9954499 | 0.85 | HDAC8 (0.51) | SMN1; SMN2KDM4ERECQLALDH1A1NAMPT | |
| SCHEMBL13188191 | 0.83 | PRKCZ (0.45) | SMN1; SMN2KDM4ERECQLALDH1A1NAMPT | |
| SCHEMBL29086059 | 0.81 | IKBKB (0.48) | ALDH1A1NAMPTHDAC8HTR1AHTR7 | |
| SCHEMBL30585992 | 0.81 | IKBKB (0.48) | ALDH1A1NAMPTHDAC8HTR1AHTR7 | |
| SCHEMBL26727086 | 0.81 | HTR1A (0.49) | SMN1; SMN2ALDH1A1NAMPTHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL21640226 | 0.80 | IKBKB (0.47) | ALDH1A1NAMPTHDAC8HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | THE SCRIPPS RESEARCH INSTITUTE | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | APEH, ALKBH3, JMJD7 | SMN1; SMN2 3965/4885KDM4E 696/4885RECQL 205/4885 |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | APEH, ALKBH3, JMJD7 | SMN1; SMN2 3965/4885KDM4E 696/4885RECQL 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.