Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.55 |
| ▸ | THRA | P10827 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586160 | 0.88 | THRB (0.41) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL30586154 | 0.83 | THRA (0.43) | THRBTHRAP2RX7 | |
| SCHEMBL30586146 | 0.82 | THRB (0.46) | THRBTHRA | |
| SCHEMBL30586143 | 0.81 | THRA (0.49) | THRBTHRA | |
| SCHEMBL30586163 | 0.81 | THRA (0.41) | THRBTHRA | |
| SCHEMBL29134028 | 0.81 | THRA (0.41) | THRBTHRA | |
| SCHEMBL30586142 | 0.81 | THRA (0.41) | THRBTHRA | |
| SCHEMBL30586145 | 0.80 | THRA (0.41) | THRBTHRAKMT2A | |
| SCHEMBL29134033 | 0.80 | THRA (0.60) | THRBTHRA | |
| SCHEMBL30586148 | 0.79 | THRA (0.42) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836158-A | Compound serving as thyroid hormone beta receptor agonist and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |