Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.46 |
| ▸ | THRA | P10827 | 15/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586154 | 0.89 | THRA (0.43) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL29134028 | 0.86 | THRA (0.41) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586142 | 0.86 | THRA (0.41) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586143 | 0.86 | THRA (0.49) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586163 | 0.86 | THRA (0.41) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL29134033 | 0.85 | THRA (0.60) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586145 | 0.85 | THRA (0.41) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586148 | 0.84 | THRA (0.42) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL30586138 | 0.82 | THRB (0.55) | THRBTHRA | |
| SCHEMBL30586147 | 0.81 | THRA (0.40) | THRBTHRACYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836158-A | Compound serving as thyroid hormone beta receptor agonist and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |