Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GABRP | O00591 | 4/20 | 0.51 |
| ▸ | GABRD | O14764 | 4/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.51 |
| ▸ | GABRE | P78334 | 4/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651755 | 1.00 | PTPN1 (0.54) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8211 | 0.89 | SMN1; SMN2 (0.56) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL29651545 | 0.88 | MIF (0.61) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8602 | 0.88 | MIF (0.61) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL10559664 | 0.84 | ALOX12 (0.63) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4366639 | 0.80 | KDM4E (0.73) | SMN1; SMN2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL18311992 | 0.78 | POLB (0.51) | PTPN1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4366282 | 0.77 | MAPT (0.74) | SMN1; SMN2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL29651565 | 0.76 | KDM4E (0.56) | SMN1; SMN2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11616373 | 0.76 | NPC1 (0.52) | PTPN1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440826-A | Administration of treatment with anti-CD 20/anti-CD 3 bispecific antibodies | 基因泰克公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-116917317-A | Administration for treatment with anti-CD 20/anti-CD 3 bispecific antibody and anti-CD 79B antibody drug conjugates | 基因泰克公司 | 2023-10-20 | — | — | CN | disclosed |