Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586191 | 0.89 | PTPN1 (0.54) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL29651755 | 0.89 | PTPN1 (0.54) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11616373 | 0.87 | NPC1 (0.52) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL18312062 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL31327833 | 0.83 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL23278859 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL31135529 | 0.81 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14994916 | 0.81 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL30620502 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL31135531 | 0.81 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | disclosed |