Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | AKT2 | P31751 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071432 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1BRD4KDRBRAF | |
| SCHEMBL3058542 | 0.79 | NOTUM (0.39) | KDM4EALDH1A1NOTUMLDHAL3MBTL1 | |
| SCHEMBL1583640 | 0.78 | NOTUM (0.41) | KDM4EALDH1A1NOTUMLDHAKDR | |
| SCHEMBL3074208 | 0.78 | CFTR (0.48) | KDM4EALDH1A1NOTUMLDHA | |
| SCHEMBL1583465 | 0.78 | NOTUM (0.42) | KDM4EALDH1A1NOTUMLDHAMRGPRX4 | |
| SCHEMBL1584276 | 0.77 | NOTUM (0.38) | KDM4EALDH1A1NOTUMLDHALMNA | |
| SCHEMBL1583159 | 0.77 | NOTUM (0.40) | KDM4EALDH1A1NOTUMLDHAMRGPRX4 | |
| SCHEMBL3691065 | 0.77 | CFTR (0.40) | KDM4EALDH1A1NOTUMLDHAKDR | |
| SCHEMBL3793277 | 0.77 | NOTUM (0.41) | KDM4EALDH1A1NOTUMLDHALMNA | |
| SCHEMBL1583734 | 0.77 | MAPT (0.37) | KDM4EALDH1A1MAPK8NOTUMLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | BASKARAN SUBRAMANIAN | 2010-10-28 | — | — | US | disclosed |
| WO-2010091411-A1 | PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | ZC3HAV1, MAVS, EIF2AK2 | KDM4E 3581/4885ALDH1A1 1772/4885MAPK8 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.