SCHEMBL30587712

SCHEMBL30587712

CON(C(=O)c1ccccc1)c1ccc(-c2ccc(I)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.42
HPGD P15428 4/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.38
KDM4E B2RXH2 2/20 0.38
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
MCHR1 Q99705 4/20 0.37
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
PTPN1 P18031 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31606638 0.95 HPGD (0.41) HPGDALDH1A1TSHRKDM4EKMT2A
SCHEMBL4526462 0.84 HPGD (0.50) HPGDALDH1A1TSHRKDM4EKMT2A
SCHEMBL30587714 0.81 NPSR1 (0.36) OXTRHPGDALDH1A1MAPTTSHR
SCHEMBL31606632 0.79 HPGD (0.48) HPGDALDH1A1KDM4EKMT2ARAB9A
SCHEMBL30587703 0.78 CES2 (0.44) ALDH1A1TSHRKDM4EKMT2ARAB9A
SCHEMBL6778056 0.78 KMT2A (0.56) HPGDALDH1A1MAPTTSHRKDM4E
SCHEMBL31606639 0.76 TP53 (0.43) HPGDALDH1A1MAPTTSHRKMT2A
SCHEMBL30587713 0.75 MAPT (0.41) OXTRHPGDALDH1A1MAPTTSHR
SCHEMBL30587701 0.75 POLB (0.49) HPGDALDH1A1TSHRKMT2ARAB9A
SCHEMBL2595456 0.74 CDC25B (0.47) OXTRHPGDALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924940-B Synthesis method of o-iodo-aniline derivative 信阳师范学院 2025-06-03 CN disclosed
CN-116924940-A Synthesis method of o-iodo-aniline derivative 信阳师范学院 2023-10-24 CN disclosed