SCHEMBL30587713

SCHEMBL30587713

CON(C(=O)c1ccccc1)c1cc(-c2ccccc2)ccc1I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
ACLY P53396 1/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.39
EGFR P00533 1/20 0.39
KMO O15229 1/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC1 Q13547 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
OXTR P30559 1/20 0.37
KAT6A Q92794 1/20 0.37
GAA P10253 1/20 0.37
HDAC3 O15379 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B2 P37059 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31606631 0.82 TSHR (0.40) ALDH1A1HPGDLMNATSHRSMN1; SMN2
SCHEMBL30587712 0.75 OXTR (0.42) MAPTALDH1A1HPGDTSHROXTR
SCHEMBL30587714 0.75 NPSR1 (0.36) MAPTALDH1A1HPGDTSHREGFR
SCHEMBL31606634 0.75 GABRP (0.40) MAPTALDH1A1HPGDLMNATSHR
SCHEMBL30587715 0.72 MEN1 (0.43) ALDH1A1HPGDTSHRMEN1KMT2A
SCHEMBL31606637 0.72 HPGD (0.47) HPGDTDP1SMN1; SMN2MEN1KMT2A
SCHEMBL30587707 0.71 HPGD (0.42) MAPTALDH1A1HPGDLMNATDP1
SCHEMBL30587709 0.71 TSHR (0.49) ALDH1A1LMNATSHRHDAC1TDP1
SCHEMBL4526462 0.70 HPGD (0.50) ALDH1A1HPGDTSHRTDP1SMN1; SMN2
SCHEMBL31606638 0.70 HPGD (0.41) ALDH1A1HPGDTSHRTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924940-B Synthesis method of o-iodo-aniline derivative 信阳师范学院 2025-06-03 CN disclosed
CN-116924940-A Synthesis method of o-iodo-aniline derivative 信阳师范学院 2023-10-24 CN disclosed