Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220092 | 1.00 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CCSNK2A1ALDH1A1 | |
| SCHEMBL10709666 | 0.86 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL7468633 | 0.82 | SLC6A4 (0.46) | CSNK2A1ALDH1A1IRAK4SLC6A2SLC6A4 | |
| SCHEMBL3160283 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL421711 | 0.82 | ALDH1A1 (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL24827553 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL17877183 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL9440903 | 0.82 | ALDH1A1 (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL225561 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL6482148 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CCSNK2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023179366-A1 | OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 星希尔生物科技(上海)有限公司 | 2023-09-28 | — | — | WO | disclosed |