Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618176 | 0.83 | CYP2D6 (0.52) | ALDH1A1LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30587766 | 0.82 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL220092 | 0.82 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL10709666 | 0.82 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1290534 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7913213 | 0.80 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL28531282 | 0.79 | LMNA (0.43) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL24827553 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL9440903 | 0.78 | ALDH1A1 (0.49) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL17877183 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | LIN, TONG-HO (TW) | 2003-03-20 | — | — | US | claimed |
| US-6846826-B2 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | Chen, Ing-Jun (TW) | 2005-01-25 | — | — | US | disclosed |
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | LIN, TONG-HO (TW) | 2003-03-20 | — | — | US | disclosed |
| US-4119729-A | TREATMENT OF HYPERTENSION | MEAD JOHNSON & COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4067904-A | ANTIARRHYTHMIA, HYPOTENSIVE | MEAD JOHNSON & COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-4054662-A | Phenoxyalkylamine containing pyridines having blood pressure reducing properties | BEIERSDORF AKTIENGESELLSCHAFT (DT) | 1977-10-18 | — | — | US | disclosed |
| US-4005096-A | HYPOTENSIVES | BIERSDORF AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3960878-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | KCNH2, ADRB3, KCNH3 | ADRA2A 43/4885ADRA2B 46/4885ADRA2C 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.